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Many drugs exhibit a linear relationship between plasma concentration and dose within the therapeutic range (dose-linear kinetics; (A); note different scales on ordinate).
The absolute configuration, as determined by certain rules, is described by the prefixes S and R. In some compounds, designation as the D- and L-form is possible by reference to the structure of D- and L-glyceraldehyde. For drugs to exert biological actions, contact with reaction partners in the body is required. |
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